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pharmachologic effect

The pharmacological effect of the drug is explained by its ability to reduce the migration of leukocytes into the inflammatory focus and inhibit the phagocytosis of uric acid salts. Buy Colchicine 0.5 mg Without Prescription The drug inhibits cell division in the metaphase and anaphase stages (partially or completely), has an anti-miotic effect, stopping neutrophil degranulation.

It prevents the development of amyloidosis, reducing the formation of amyloid fibrils. Colchicine is a highly effective way to prevent gout attacks. This drug shows its effectiveness in more than 75% of cases in the first 12 hours of use..

Colchicine and similar drugs

Preparations based on the active substance Colchicine are produced in China and Europe. Substances with similar effects may vary in price. Instead of colchicine, Ambene, Revmador, Naproxen and other options can be used to treat gout..

Ambene Naproxen Fullflex


Colchicine tablets should not be taken by people with serious pathologies in the digestive tract, heart, blood vessels, neutropenia, bone marrow diseases, during the development of purulent infection, during gestation and in children under six years of age.

If the patient has problems with the performance of the liver and kidneys, then the toxic substance will begin to accumulate in the body, poisoning it. Therefore, in case of serious violations in the work of these organs, you should refrain from taking the medication.

The drug is not suitable for people who have a high sensitivity to colchicine. Pills in this case should not be drunk.

Colchicine treatment is contraindicated in chronic alcoholics, as the toxic effect on the body will increase. Caution should be taken with colchicine tablets for the elderly.

What is dangerous overdose?

When taking large doses of the drug, the body is intoxicated with its medicinal substances. http://en.m.wikipedia.org/wiki/Colchicine As a result, the following symptoms appear:


  • gagging;
  • nausea;
  • diarrhea;
  • severe pain in the abdomen and oral cavity;
  • burning of the skin;
  • the appearance of blood in urine;
  • cramps.


An overdose of the described medication can lead to acute renal failure and severe bone marrow suppression, accompanied by a decrease in the number of white blood cells and platelets in the blood. Poisoning the body with the chemicals of the drug can worsen blood coagulation. In this case, the victim will need to be hospitalized in a toxicological center, where airway patency, additional ventilation and maintenance of vital functions are monitored..